||E. van der Pol|
||Photonics Event 2015, Veldhoven, The Netherlands|
||June 4, 2015|
Exosomes are cell-derived extracellular vesicles which are abundantly present in human body fluids. Since the size, concentration and composition of these vesicles change during disease, vesicles have promising clinical applications. However, due to their small size (<1 μm), vesicle detection is challenging and clinical applications are not realized yet. This lecture describes the recent advancements of vesicle detection with optical techniques, including flow cytometry, Raman microspectroscopy, and single particle tracking. To cap it all, a world record in the optical detection of single vesicles in suspension will be presented.