Articles

The list below contains articles to which I contributed. For metrics, please check my profiles at Google Scholar, Publons, and ORCID

2025

076 Targeting oncofoetal chondroitin sulphate allows identification of tumour-derived extracellular vesicles (pdf, 3 MB)
Agustin Enciso-Martinez, Caroline Lřppke, Joyce J. Koene, Jade Ebbelaar, Meike van der Geest, Mandy Los, Emma P.E.M. Boerrigter, Robert Dagil, Tobias Gustavsson, Elena E. Vidal-Calvo, Ton G. van Leeuwen, Roman I. Koning, Nick van Es, Ali Salanti, Edwin van der Pol, Rienk Nieuwland, Mette Ř. Agerćk, and Peter ten Dijke
Journal of Extracellular Vesicles 14 (6), e70106 (2025)

2024

075 Endothelial cell-derived extracellular vesicles allow to differentiate between various endotypes of INOCA: a multicentre, prospective, cohort study (pdf, 2 MB)
Aleksandra G?secka, Piotr Szolc, Edwin van der Pol, ?ukasz Niewiara, Bart?omiej Guzik, Pawe? Kleczy?ski, Mariusz Tomaniak, Emilia Figura, Mateusz Zaremba, Marcin Grabowski, Janusz Kochman, Jacek Legutko, and ?ukasz Ko?towski
Journal of Cardiovascular Translational Research, in press.
074 Size and fluorescence calibrated imaging flow cytometry: from arbitrary units to standard units (pdf, 1 MB)
Wouter W. Woud, Haley R. Pugsley, Britta A. Bettin, Zoltán Varga, and Edwin van der Pol
Cytometry Part A 105 (10), 752-762 (2024)
073 Leukocyte extracellular vesicles predict progression of systolic dysfunction in heart failure with mildly reduced ejection fraction (LYCHEE) – a prospective, multicentre cohort study (pdf, 1 MB)
Aleksandra G?secka, Aleksander Siniarski, Piotr Duchnowski, Ewelina B?a?ejowska, Magdalena Gajewska, Kacper Karaban, Kinga Por?bska, Aleksandra Reda, Sylwester Rogula, Bartosz Rolek, Dorota S?upik, Roksana Gozdowska, Marcin Kleibert, Dominika Zajkowska, Micha? Gr?t, Marcin Grabowski, Krzysztof J. Filipiak, Edwin van der Pol, and Rienk Nieuwland
Journal of Cardiovascular Translational Research, in press.
072 Choice of size-exclusion chromatography column affects recovery, purity, and miRNA cargo analysis of extracellular vesicles from human plasma (pdf, 3 MB)
Jillian W.P. Bracht, Mandy Los, Edwin van der Pol, Sandra A.W.M. Verkuijlen, Monique A.J. van Eijndhoven, D. Michiel Pegtel, and Rienk Nieuwland
Extracellular Vesicles and Circulating Nucleic Acids 5 (3), 497-08 (2024)
071 Extracellular vesicles to predict outcomes after transcatheter aortic valve implantation – a prospective, multicenter cohort study (pdf, 2 MB)
Rados?aw Wilimski, Jan Budzianowski, Micha? ?omiak, Anna Olasi?ska?Wi?niewska, Katarzyna Pieniak, Szymon J?drzejczyk, Olaf Domaszk, Magdalena Chudzik, Krzysztof J. Filipiak, Jaros?aw Hiczkiewicz, Wojciech Faron, Tomasz Urbanowicz, Marek Jemielity, Marek Grygier, Marcin Grabowski, Mariusz Ku?mierczyk, Bartosz Rymuza, Zenon Huczek, Janusz Kochman, Edwin van der Pol, Rienk, Nieuwland, and Aleksandra G?secka
Journal of Cardiovascular Translational Research 17 (5), 992-1003 (2024)
070 Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches (external)
Joshua A. Welsh, Deborah C.I. Goberdhan, Lorraine O'Driscoll, Edit I. Buzas, Cherie Blenkiron, Benedetta Bussolati, Houjian Cai, Dolores Di Vizio, Tom A.P. Driedonks, Uta Erdbrügger, Juan M. Falcon-Perez, Qing-Ling Fu, Andrew F. Hill, Metka Lenassi, Sai Kiang Lim, M? G. Mahoney, Sujata Mohanty, Andreas Möller, Rienk Nieuwland, Takahiro Ochiya, Susmita Sahoo, Ana C. Torrecilhas, Lei Zheng, Andries Zijlstra, Sarah Abuelreich et al.
Journal of Extracellular Vesicles 13 (2), e12404 (2024)
069 Poloxamer-188 as a wetting agent for microfluidic resistive pulse sensing measurements of extracellular vesicles (pdf, 2 MB)
Mona Shahsavari, Rienk Nieuwland, Ton G. van Leeuwen, and Edwin van der Pol
Plos One 19 (5), e0295849 (2024)
068 Lipoprotein apheresis affects the concentration of extracellular vesicles in patients with elevated lipoprotein (a) (pdf, 2 MB)
Joanna Marl?ga-Linert, Aleksandra G?secka, Edwin van der Pol, Agnieszka Kuchta, Krzysztof J. Filipiak, Marcin Fija?kowski, Marcin Grucha?a, Rienk Nieuwland, and Agnieszka Mickiewicz
Scientific Reports 14, 2762 (2024)
067 Traceable characterization of hollow organosilica beads as potential reference materials for extracellular vesicle measurements with optical techniques (pdf, 3 MB)
Jérôme Deumer, Robin Schürmann, Anikó Gaál, Zoltán Varga, Britta Bettin, Edwin van der Pol, Rienk Nieuwland, David Ojeda, Aneta Sikora, Dorota Bartczak, Heidi Goenaga?Infante, Johanna Noireaux, Mahrad Khakpour, Virpi Korpelainen, and Christian Gollwitzer
Discover Nano 19 (1), 14 (2024)

2023

066 MicroRNAs in extracellular vesicles released from epicardial adipose tissue promote arrhythmogenic conduction slowing (pdf, 3 MB)
Auriane C. Ernault, Rosan de Winter, Benedetta Fabrizi, Jillian WP Bracht, Chi Hau, Shirley CM van Amersfoorth, Eva R. Meulendijks, Anke J. Tijsen, Lucía Cócera Ortega, Ingeborg van der Made, Aleksandra Gasecka, Antoine H. Driessen, Rienk Nieuwland, Bastiaan J. Boukens, Edwin van der Pol, Joris R. de Groot, and Ruben Coronel
Heart Rhythm O2 4 (12), 805-14 (2023)
065 Plasma extracellular vesicle test sample to standardize flow cytometry measurements (pdf, 1 MB)
Britta Bettin, Edwin van der Pol, and Rienk Nieuwland
Research and Practice in Thrombosis and Haemostasis 7 (4), 100181 (2023)
064 Benchmarking blood collection tubes and processing intervals for extracellular vesicle performance metrics (pdf, 4 MB)
Bert Dhondt, Cláudio Pinheiro, Edward Geeurickx, Joeri Tulkens, Glenn Vergauwen, Edwin van der Pol, Rienk Nieuwland, Anneleen Decock, Ilkka Miinalainen, Pekka Rappu, Jo Vandesompele, Pieter Mestdagh, Nicolaas Lumen, Olivier de Wever, and An Hendrix
Journal of Extracellular Vesicles 12 (5), 12315 (2023)
063 Preventing swarm detection in extracellular vesicle flow cytometry - a clinically applicable procedure (pdf, 2 MB)
Naomi C. Buntsma, Mona Shahsavari, Aleksandra G?secka, Rienk Nieuwland, Ton G. van Leeuwen, and Edwin van der Pol
Research and Practice in Thrombosis and Haemostasis 7 (4), 100171 (2023)
062 Standardization of extracellular vesicle concentration measurements by flow cytometry: the past, present and future (pdf, 1 MB)
Britta Bettin, Zoltán Varga, Rienk Nieuwland, and Edwin van der Pol
Journal of Thrombosis and Haemostasis 21 (8), 2032-44 (2023)
061 Isolation-free measurement of single urinary extracellular vesicles by imaging flow cytometry (pdf, 3 MB)
Liang Wu, Wouter W. Woud, Carla C. Baan, Dennis A. Hesselink, Edwin van der Pol, Guido Jenster, and Karin Boer
Nanomedicine: Nanotechnology, Biology and Medicine 48, 102638 (2023)
060 A compendium of single extracellular vesicle flow cytometry (pdf, 4 MB)
Joshua A. Welsh, Ger J.A. Arkesteijn, Michel Bremer, Michael Cimorelli, Françoise Dignat-George, Bernd Giebel, André Görgens, An Hendrix, Martine Kuiper, Romaric Lacroix, Joanne Lannigan, Ton G. van Leeuwen, Estefanía Lozano-Andrés, Shoaib Rao, Stéphane Robert, Leonie de Rond, Vera A. Tang, Tobias Tertel, Xiaomei Yan, Marca H.M. Wauben, John Nolan, Jennifer C. Jones, Rienk Nieuwland, and Edwin van der Pol
Journal of Extracellular Vesicles 12 (2), 12299 (2023)
059 Platelet removal from human blood plasma improves detection of extracellular vesicle-associated miRNA (pdf, 1 MB)
Jillian W.P. Bracht, Mandy Los, Monique A.J. van Eijndhoven, Britta Bettin, Edwin van der Pol, D. Michiel Pegtel, and Rienk Nieuwland
Journal of Extracellular Vesicles 12 (2), 12302 (2023)

2022

058 Automated fluorescence gating and size determination reduce variation in measured concentration of extracellular vesicles by flow cytometry (pdf, 1 MB)
Angela A.F. Gankema, Bo Li, Rienk Nieuwland, and Edwin van der Pol
Cytometry Part A 101 (12), 1049-56 (2022)
057 Shock-driven endotheliopathy in trauma patients is associated with leucocyte derived extracellular vesicles (pdf, 1 MB)
Romein WG Dujardin, Jeske EC Kisters, Mathijs R. Wirtz, Najat Hajji, Anita M. Tuip-de Boer, Jakob Stensballe, Pär I. Johansson, Karim Brohi, Ross A. Davenport, Christine Gaarder, Simon Stanworth, Marc Maegele, Rienk Nieuwland, Edwin van der Pol, and Nicole P. Juffermans
International Journal of Molecular Sciences 23 (24), 15990 (2022)
056 Removal of platelets from blood plasma to improve the quality of extracellular vesicle research (pdf, 1 MB)
Britta Bettin, Aleksandra Gasecka, Bo Li, Bert Dhondt, An Hendrix, Rienk Nieuwland, and Edwin van der Pol
Journal of Thrombosis and Haemostasis 20 (11), 2679-85 (2022)
055 Method to traceably determine the refractive index by measuring the angle of minimum deviation (pdf, 1 MB)
Martine Kuiper, Richard Koops, Rienk Nieuwland, and Edwin van der Pol
Metrologia 59 (5), 055006 (2022)
054 EDTA stabilizes the concentration of platelet-derived extracellular vesicles during blood collection and handling (pdf, <1 MB)
Naomi C. Buntsma, Aleksandra G?secka, Yvo B.W.E.M. Roos, Ton G. Leeuwen, Edwin, van der Pol, and Rienk Nieuwland
Platelets 33 (5), 764-71 (2022)
053 An imaging flow cytometry-based methodology for the analysis of single extracellular vesicles in unprocessed human plasma (pdf, 3 MB)
Wouter W. Woud, Edwin van der Pol, Erik Mul, Martin J. Hoogduijn, Carla C. Baan, Karin, Boer, and Ana Merino
Communications Biology 5 (633), 1-4 (2022)
052 Calibration and standardization of extracellular vesicle measurements by flow cytometry for translational prostate cancer research (pdf, 4 MB)
Yohan Kim, Edwin van der Pol, Ali Arafi, Ishwor Thapa, Cameron Britton, Jorgena Kosti, Siyang Song, Vidhu B. Joshi, Ree Erickson, Hesham Ali, and Fabrice Lucien
Nanoscale 14, 9781-95 (2022)